Hope Generation Foundation Research Center

This center is mainly focused on the translational and applied research. At present there are several projects underway, all designed and directed by Dr Ghaffari.

List of Projects Since 2015:

2018-present   Collaborative Project: Hope Generation Foundation Ministry of Health and Medical Education   Targeted next generation sequencing of known genes associated with mucopolysaccharidosis in 320 patients registered in Iran Food and Drug Organization
2018-present   Collaborative Project: Hope Generation Foundation Vali E-Asr Rehabilitation Foundation Hope Project: genetic profiling of 2500 patients with genetic disorders to determine the distribution of mutations in different Iran provinces   Phase 1: attracted 700,000 $ 1000 patients with inborn errors of metabolism and hereditary eye disorders  
2017-present   Collaborative Project: Hope Generation Foundation Iran RP Society Genetic Profiling of Iranian patients with inherited retinal disorders using targeted next generation sequencing of 316 known genes associated with hereditary eye disorders    
2017-present   Collaborative Project: Hope Generation Foundation Iran Hemophilia Center A comprehensive genetic approach to 100 Iranian patients with Glanzmann thrombasthenia by mutation analysis of known related genes using targeted next generation sequencing    
2017-present   Hope Generation Foundation   Clinical Application of Next Generation Sequencing in Personalized Medicine: Simultaneous Investigation of Somatic Point Mutations, Copy Number Variations and Cytogenetic Rearrangements (fusion proteins) using Oncomine Comprehensive Cancer Panel    
2015-present   Hope Generation Foundation Avicenna Research Institute Determining the Distribution of Genetic Causes among Iranian Patients with Premature Ovarian Insufficiency using a Comprehensive Algorithm with a Specific Approach to Single Gene Disorders by Whole Exome Sequencing    
2016-present   Collaborative Project: Hope Generation Foundation Vali E-Asr Rehabilitation Foundation   Determining the Genetic Causes of Familial Cerebral Palsy using Whole Exome Sequencing   Attracted 30,000$
2015-present   Hope Generation Foundation   Assessment of Single Gene Disorders in Familial Intellectual Disability by Whole Exome Sequencing
2017-present   Hope Generation Foundation Development, Optimization and validation of Copy Number Variation Analysis using Whole Exome Sequencing Data (Exome-Array)
2016-2017   Hope Generation Foundation Avicenna Research Institute Development and Optimization of Preimplantation High Resolution HLA Typing (8-digit) using Next Generation Sequencing (PGD-HLA-NGS)  
2015-2016   Hope Generation Foundation Avicenna Research Institute Development and Optimization of PGS-NGS: Preimplantation Genetic Screening of All Chromosomal Aneuploidies using Next Generation Sequencing (Single Cell Whole Genome Amplification Followed by Low-Pass NGS Aneuploidy Detection)
2015-2016   Hope Generation Foundation Iranian Blood Transfusion Organization Development and Optimization of HLA Typing using Next Generation Sequencing
2015   Hope Generation Foundation Design the Specific Gene Sets for Targeted Next Generation Sequencing in Heterogenous Disorders (Intellectual Disability, Hearing Impairment, Retinitis Pigmentosa, Neuromuscular Disorders, Genodermatoses, …)

Be the first to comment

Leave a Reply

Your email address will not be published.


*